Higher education institutions are entering the next wave of the AI revolution, moving beyond student use of ChatGPT to leveraging predictive and generative AI for institutional transformation. This playbook provides a strategic framework for implementing AI across recruitment, admissions, student success, and advancement functions. The key to successful AI adoption lies in establishing trusted, unified data as the foundation for both predictive insights and generative actions. Institutions can use AI to personalize communications at scale, automate routine tasks, and proactively address student needs throughout the entire lifecycle.